Multiple sclerosis (MS) is a chronic immune-mediated, inflammatory
demyelinating disease of the central nervous system (CNS) that affects both thebrain and spinal cord. The cause of MS is not fully understood, but the disease
is believed to relate to an abnormal immune response in individuals who are
genetically predisposed.
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| Multiple Sclerosis |
An association of personal predisposition and environmental conditions
may result in immune-mediated inflammation of the CNS and culminate in neuronal
loss. The disease usually manifests in bouts of neurological disabilities and
later progresses to dysfunction of many areas of the CNS. It can affect motor
and sensory functions, coordination, cognition, and vision and sphincter
control. It is often associated with fatigue, pain, depression, and anxiety and
sleep disorders, thus leading to considerable personal, social and economic
losses. Lifestyle/environmental factors may have an important role in
determining the risk of MS. These are harder to accurately study and quantify than
are genetic factors. However, it is important to identify these potential
determinants of risk and worse outcomes in MS, since they are potentially
preventable. Depression, anxiety disorders, social withdrawal and cognitive
deficits often affect the quality of life of patients with MS. Chronic diseases
like MS may negatively affect friendships and family relations. Read more>>>>>>>>>
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